Simvastatin

Simvastatin is a medicine used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition, Simvastatin raises levels of “good” cholesterol (HDL cholesterol). Simvastatin is a member of the class of medicines called statins.

Simvastatin Tablets

Simvastatin 10mg

NOTE: Generic medication. Brand may vary from the picture shown.

£19.97
includes free private prescription
£24.97
includes free private prescription

Simvastatin 20mg

NOTE: Generic medication. Brand may vary from the picture shown.

£19.97
includes free private prescription
£24.97
includes free private prescription

Simvastatin 40mg

NOTE: Generic medication. Brand may vary from the picture shown.

£19.97
includes free private prescription
£24.97
includes free private prescription

Simvastatin 80mg

NOTE: Generic medication. Brand may vary from the picture shown.

£29.97
includes free private prescription
£34.97
includes free private prescription

What's Simvastatin?

Simvastatin is a medicine used to lower levels of total cholesterol, “bad” cholesterol (LDL cholesterol), and fatty substances called triglycerides in the blood. In addition, Simvastatin raises levels of “good” cholesterol (HDL cholesterol). Simvastatin is a member of the class of medicines called statins.

Cholesterol is one of several fatty substances found in the bloodstream. Your total cholesterol is made up mainly of LDL and HDL cholesterol.

LDL cholesterol is often called “bad” cholesterol because it can build up in the walls of your arteries forming plaque. Eventually this plaque build-up can lead to a narrowing of the arteries. This narrowing can slow or block blood flow to vital organs such as the heart and brain. This blocking of blood flow can result in a heart attack or stroke.

HDL cholesterol is often called “good” cholesterol because it helps keep the bad cholesterol from building up in the arteries and protects against heart disease.

Triglycerides are another form of fat in your blood that may increase your risk for heart disease.

You should stay on a cholesterol-lowering diet while taking this medicine.

Always take Simvastatin exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Remember to keep to a low-fat diet and exercise while taking simvastatin.
Keep taking the medicine until your doctor tells you to stop.

Always swallow the tablets with plenty of water.

You should not drink grapefruit juice when you are taking simvastatin. It may increase the amount of simvastatin in your blood and could increase the risk of muscle problems.

Do not take Simvastatin

  • if you are allergic (hypersensitive) to simvastatin or any of the other ingredients of this medicine (listed in Section 6: Contents of the pack and other information).
  • if you currently have liver problems
  • if you are pregnant or breast-feeding
  • if you are taking medicine(s) with one or more than one of the following active ingredients: o itraconazole, ketoconazole, posaconazole or voriconazole (used to treat fungal infections)
    • erythromycin, clarithromycin, or telithromycin ( used to treat infections)
    • HIV protease inhibitors such as indinavir, nelfinavir, ritonavir, and saquinavir (HIV protease inhibitors are used for HIV infections)
    • boceprevir or telaprevir (used to treat hepatitis C virus infection)
    • nefazodone (used to treat depression)
    • gemfibrozil (used to lower cholesterol)
    • ciclosporin (used in organ transplant patients)
    • danazol (a man-made hormone used to treat endometriosis, a condition in which the lining of the uterus grows outside the uterus).
  • if you are taking or, in the last 7 days, have taken or been given a medicine called fusidic acid (used to treat bacterial infection)

Ask your doctor if you are not sure if your medicine is listed above.

Like all medicines, simvastatin can cause side effects, although not everybody gets them.

Stop taking Simvastatin and see a doctor or go to a hospital straight away if:

  • You experience symptoms of angioedema, such as swollen face, tongue or throat, difficulty breathing and swallowing or hives
  • You get unexplained pain, tenderness or weakness in the muscles or pain or inflammation in your joints, high temperature or tiredness
  • Inflammation of the blood vessels
  • Unusual bruising, swelling, skin sensitivity to the sun
  • You get a lumpy rash or flushing of the skin
  • You get liver problems, such as yellowing of the skin or eyes (jaundice/hepatitis)
  • Dark coloured urine or pale coloured stool, liver failure (very rare)
  • You experience severe abdominal pain which may be caused by an inflamed pancreas (pancreatitis)

Medical Advice

Please refer to the articles below to find out more information, medical guidance and advice from our doctors on how to best treat the condition.
Learn about available treatments, symptoms, side effects and what you can do to prevent it.

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