Orlistat is a type of medicine called a lipase inhibitor. Orlistat is used to treat obesity.
It works in your digestive system to block about one-third of the fat in the food you eat from being digested.

Orlistat 120mg Capsules

Orlistat 120mg Capsules

Orlistat is a medicine used to treat obesity. It works in your digestive system to block about one-third of the fat in the food you eat from being digested. Orlistat attaches to the enzymes in your digestive system (lipases) and blocks them from breaking down some of the fat you have eaten during your meal. The undigested fat cannot be absorbed and is eliminated by your body. Orlistat is indicated in the treatment of obesity in conjunction with a low calorie intake diet.

NOTE: Generic medication. Brand may vary from the picture shown.

includes free private prescription
includes free private prescription
includes free private prescription

What is Orlistat?

When the human body needs to break down fat, it employs the use of an enzyme called lipase; this is the enzyme to which Orlistat fastens itself to. For the body to readily filter in fat, it has to be broken down, or else it passes out of the body as faeces. This simply implies that Orlistat is highly effective in preventing weight gain; but is not known to help you lose the weightiness you have already gained. Besides, consumption of meals that is saturated with fat, when used with Orlistat, is the root cause of very nasty side effects. This is why it is advised that the person who intends to take orlistat should already be following a suitable weight-loss regime.

In the United Kingdom, orlistat is the only medication that is prescribed for losing weight. Assessment of recent studies indicates that people who were already on a low calorie intake of food lost an average of about 8.1kg (1.25stone) after one year of using orlistat; this is about 2.8kg (6stone) more than those who did not use orlistat. A two-year study also revealed that people who used orlistat lost about 10% of their body weight within just one year when combined with low-calorie nutrition.

If you eat an excessive amount of fat or calories, the excess is stored as fat by the body, resulting in weight gain. When you eat fat, your body breaks it down into its simplest components so that it can be digested.

Unlike other weight-loss drugs you may have heard about that act in the brain or central nervous system to suppress appetite or to speed up metabolism, Orlistat works in your digestive system to block about one-third of the fat in the food you eat from being digested.Enzymes in your digestive system, called lipases, help digest (or break down) fat.

When taken with meals, Orlistat attaches to the lipases and blocks them from breaking down some of the fat you have eaten.The undigested fat cannot be absorbed and is eliminated in your bowel movements. By working this way, Orlistat helps block about one-third of the fat in the foods you eat from being absorbed by your body.

There are some people who are advised to keep away from orlistat. These groups of people are:

  • Expectant or nursing mothers
  • People that are under the age of 18
  • People with aversions or sensitivities
  • People with food absorption challenges
  • People who have a bile-liver health problem.

For continued usage or orlistat, you must have lost at least 5% of your body weight after 3 months; this percentage may be lower if you are suffering from type-2 diabetes. This is because people with diabetes usually take longer to lose weight. Orlistat can be prescribed for you up to a year; that is if your doctor is fully satisfied with your progress after about 3 months. Afterwards, your doctor needs to evaluate you to check for improvements.

Orlistat may be right for you if you have a Body Mass Index of 30 or greater, or have a BMI of 27 or greater and have other risk factors, such as high blood pressure, high cholesterol, heart disease or diabetes.

For orlistat to work effectively, it must be taken 3 times daily after each meal, which has at least 30% of it made up of fat. You either use the medication while you are still eating your meal, or take it an hour after the meal. But if perhaps, your meal has no fat content, you may avoid taking your orlistat does for that meal.

For orlistat to be very effective, it must be part of a comprehensive package that includes nutrition, workouts and control of weight. Daily consumption of your meals must contain an even spread of protein, fat and carbohydrates. The medication, food regime and workout must be followed religiously.

Ensure that the fat content of your food on a daily basis does not exceed 30% of your overall day-to-day consumption. That means you should endeavour to find out how much fat your choice foods contain, in order to be able to plan your daily consumption pattern. You could do this by checking the labels. Doing this will make you know just how much fat you need to consume per meal, and you should also avoid saving fat from one meal, only to eat it all up in the next meal. Each meal or snack must have the appropriate fat requirement.

Do not take Orlistat:

  • if you are allergic (hypersensitive) to orlistat or to any of the other ingredients of Orlistat,
  • if you have chronic malabsorption syndrome (insufficient absorption of nutrients from alimentary tract),
  • if you have cholestasis (liver disorder)
  • if you are breast-feeding
Unlike other commonly prescribed weight-loss medications, Orlistat is not an appetite suppressant and does not have a direct effect on the brain. Instead, it works in your digestive system to block about one third of the fat in the food you eat from being digested.
All medicines have side effects, and orlistat is not an exception in this regard. Indeed, orlistat also has the effects it causes aside its primary assignment, not everyone is usually affected by them.

The most of these side effects is the recurrent bowel movements and passing out of soft faeces and oily spotting. This is usually the result of the tablet as it works in making sure your body passes out the excess fat in your body. This typically happens in the first few weeks when you have not yet learnt to adjust your fat intake when you consume your meals. In a way, this frequent bowel movement or soft stools lets you know that you may have eaten more fat than your body requires; for this reaction is based on what you eat per time. So in order to reduce these unpleasant physical discomforts, control the way you consume your food by eating lower-fat meals.

Orlistat has been known to interfere with the way other medicines work within the body. They are outlined below:

  • HIV and AIDS treatements
  • Acarbose
  • Ciclosporin
  • Amiodarone
  • Warfarin
  • Epilepsy treatments (not all, though)

Contraceptive pills are also affected when used together with orlistat; such interference is usually caused when you pass out so much soft stools that the pills don’t have the time to get absorbed in to the body. You may follow any of the following advice if you want to keep using orlistat:

  • You should seek other methods of birth control or contraception, which includes but not limited to the use of condoms when you decide to orlistat; that is if you pass out stools incessantly, which will prevent the absorption of any contraceptive pill.
  • Inform your doctor or your pharmacist about any other medication you may be on before embarking on the use of orlistat.
  • You may also use a multivitamin that will enhance your daily intake of vitamin. You should do this when you are about to go to bed, and when you will not be taking orlistat.

Before you even start using orlistat, make sure you read the leaflet in the packet to see and know about the precautions to take and the full list of people who should or should not use orlistat.

Medical Advice

Please refer to the articles below to find out more information, medical guidance and advice from our doctors on how to best treat the condition.
Learn about available treatments, symptoms, side effects and what you can do to prevent it.

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